Publications
Main Publications
Ramos‑Rodríguez, Mireia, Subirana‑Granés, M., Norris, R., Sordi, V., Fernández, Á., Fuentes‑Páez, G., Pérez‑ González, B., Berenguer Balaguer, C., Raurell‑Vila, H., Chowdhury, M., Corripio, R., Partelli, S., López‑Bigas, N., Pellegrini, S., Montanya, E., Nacher, M., Falconi, M., Layer, R., Rovira, M., … Pasquali, L. (2024). Implications of noncoding regulatory functions in the development of insulinomas. Cell Genomics, 4(8), 100604. https://doi.org/10.1016/j.xgen.2024.100604
Ramos‑Rodríguez, Mireia, Subirana‑Granés, M., & Pasquali, L. (2021). UMI4Cats: An R package to analyze chromatin contact profiles obtained by UMI‑4C. Bioinformatics. https://doi.org/10.1093/bioinformatics/btab392
Ramos‑Rodríguez, Mireia, Pérez‑González, B., & Pasquali, L. (2021). The β‑Cell Genomic Landscape in T1D: Implications for Disease Pathogenesis. Current Diabetes Reports, 21(1), 1. https://doi.org/10.1007/s11892-020-01370-4
Ramos‑Rodríguez, Mireia, Raurell‑Vila, H., Colli, M. L., Alvelos, M. I., Subirana‑Granés, M., Juan‑Mateu, J., Norris, R., Turatsinze, J.‑V., Nakayasu, E. S., Webb‑Robertson, B.‑J. M., Inshaw, J. R. J., Marchetti, P., Piemonti, L., Esteller, M., Todd, J. A., Metz, T. O., Eizirik, D. L., & Pasquali, L. (2019). The impact of proinflammatory cytokines on the β‑cell regulatory landscape provides insights into the genetics of type 1 diabetes. Nature Genetics, 51(11), 1588–1595. https://doi.org/10.1038/s41588-019-0524-6
Mularoni, L., Ramos‑Rodríguez, Mireia, & Pasquali, L. (2017). The Pancreatic Islet Regulome Browser. Frontiers in Genetics, 8(FEB), 13. https://doi.org/10.3389/fgene.2017.00013
Collaborations
Sarkar, S., Deiter, C., Kyle, J. E., Guney, M. A., Sarbaugh, D., Yin, R., Li, X., Cui, Y., Ramos‑Rodriguez, Mireia, Nicora, C. D., Syed, F., Juan‑Mateu, J., Muralidharan, C., Pasquali, L., Evans‑Molina, C., Eizirik, D. L., Webb‑ Robertson, B.‑J. M., Burnum‑Johnson, K., Orr, G., … Nakayasu, E. S. (2024). Regulation of β‑cell death by ADP‑ribosylhydrolase ARH3 via lipid signaling in insulitis. Cell Communication and Signaling, 22(1), 141. https://doi.org/10.1186/s12964-023-01437-1
Fontcuberta‑PiSunyer, M., Garcı́ a‑Alamán, A., Prades, Èlia, Téllez, N., Alves‑Figueiredo, H., Ramos‑Rodríguez, Mireia, Enrich, C., Fernandez‑Ruiz, R., Cervantes, S., Clua, L., Ramón‑Azcón, J., Broca, C., Wojtusciszyn, A., Montserrat, N., Pasquali, L., Novials, A., Servitja, J.‑M., Vidal, J., Gomis, R., & Gasa, R. (2023). Direct reprogramming of human fibroblasts into insulin‑producing cells using transcription factors. Communications Biology, 6(1). https://doi.org/10.1038/s42003-023-04627-2
Arroyo, N., Villamayor, L., Díaz, I., Carmona, R., Ramos‑Rodríguez, Mireia, Muñoz‑Chápuli, R., Pasquali, L., Toscano, M. G., Martín, F., Cano, D. A., & Rojas, A. (2021). GATA4 induces liver fibrosis regression by deac‑ tivating hepatic stellate cells. JCI Insight, 6(23). https://doi.org/10.1172/jci.insight.150059
Colli, M. L., Ramos‑Rodríguez, Mireia, Nakayasu, E. S., Alvelos, M. I., Lopes, M., Hill, J. L. E., Turatsinze, J.‑ V., Brachène, A. C. de, Russell, M. A., Raurell‑Vila, H., Castela, A., Juan‑Mateu, J., Webb‑Robertson, B.‑J. M., Krogvold, L., Dahl‑Jorgensen, K., Marselli, L., Marchetti, P., Richardson, S. J., Morgan, N. G., … Eizirik, D. L. (2020). An integrated multi‑omics approach identifies the landscape of interferon‑mediated responses of human pancreatic beta cells. Nature Communications 2020 11:1, 11(1), 1–17. https://doi.org/10.1038/s41467-020-16327-0
Miguel‑Escalada, I., Bonàs‑Guarch, S., Cebola, I., Ponsa‑Cobas, J., Mendieta‑Esteban, J., Atla, G., Javierre, B. M., Rolando, D. M. Y., Farabella, I., Morgan, C. C., García‑Hurtado, J., Beucher, A., Morán, I., Pasquali, L., Ramos‑Rodríguez, Mireia, Appel, E. V. R., Linneberg, A., Gjesing, A. P., Witte, D. R., … Ferrer, J. (2019). Human pancreatic islet three‑dimensional chromatin architecture provides insights into the genetics of type 2 diabetes. Nature Genetics, 51(7), 1137–1148. https://doi.org/10.1038/s41588-019-0457-0
Kameswaran, V., Golson, M. L., Ramos‑Rodríguez, Mireia, Ou, K., Wang, Y. J., Zhang, J., Pasquali, L., & Kaest‑ ner, K. H. (2018). The Dysregulation of the DLK1 ‑ MEG3 Locus in Islets From Patients With Type 2 Diabetes Is Mimicked by Targeted Epimutation of Its Promoter With TALE‑DNMT Constructs. Diabetes, 67(9), 1807–1815. https://doi.org/10.2337/db17-0682
PhD Thesis
Book Chapters
Raurell‑Vila, H., Ramos‑Rodríguez, Mireia, & Pasquali, L. (2018). Assay for Transposase Accessible Chromatin (ATAC‑Seq) to Chart the Open Chromatin Landscape of Human Pancreatic Islets. In T. Vavouri & M. A. Peinado (Eds.), Methods in molecular biology (CpG Island, pp. 197–208). Human Press. https://doi.org/10.1007/978-1-4939-7768-0_11